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had a serum calcitonin level (at visit 1) of 20 ng l 1 , if eGFR 60 ml min 1 1.73 m 2 35 ng l 1 , if eGFR 2 weeks or 14 days) systemic glucocorticoid therapy (excluding topical, intraocular, intranasal, intra-articular or inhaled preparations) or had evidence of a substantial, active autoimmune abnormality (for example, lupus or rheumatoid arthritis) that had required (within the past 3 months) or was likely to require, in the opinion of the investigator, concurrent treatment with systemic glucocorticoids (excluding topical, intraocular, intranasal, intra-articular or inhaled preparations) during the course of the study 33

Patients were randomized in a 1:1:1 ratio to once weekly fixed dosage of ZEPBOUND 10 mg, ZEPBOUND 15 mg, or placebo with an escalation period of up to 20 weeks followed by the maintenance period

Individual results vary, and no specific outcome is guaranteed

Extensive Tirzepatide Dosing Calculator FAQ This section provides in-depth answers to common and complex questions asked by research teams and informed peptide buyers

Step 6: Slowly depress the plunger until all the solution is injected, then withdraw the needle smoothly