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Description
GLP-1 medications such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have changed the way we treat obesity and metabolic disease
The mechanism of DPP-4 inhibitors is to increase incretin levels (GLP-1 and GIP), [2] [3] [4] which inhibit glucagon release, which in turn increases insulin secretion, decreases gastric emptying, and decreases blood glucose levels
Key Players/ Company Profile 21.1
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12 Zhou, L., Qu, H., Yang, L., & Shou, L
This hormone signals by binding to and activating GCGR, which is a G protein-coupled receptor primarily expressed by hepatocytes in the liver
