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Sustained Weight Maintenance: The SCALE Maintenance trial demonstrated that 81.4% of Liraglutide-treated patients maintained their initial 5% weight loss, compared to only 48.9% of placebo-treated patients , proving its effectiveness for long-term weight management rather than just initial loss

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16 Finally, compared to other GLP-1 receptor agonists like dulaglutide, semaglutide is generally more potent, longer-acting, and often leads to greater HbA1c reductions and weight loss

Last reviewed: May 14, 2026 Last updated: May 14, 2026 Written by: Jay Hastings | Reviewed by: Jayden Lee, PharmD Fella Health is one of many telehealth programs in the GLP-1 / weight management space

Yet, as others have noted, there is not compelling evidence that this is specific to Ozempic, but rather is presumed to be a normative consequence of weight loss regardless of the method ( Peters et al