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Description
Rebounding is a problem in all kinds of bariatric therapy, but if GLP-1 patients dont incorporate exercise into their routine, they are at risk of an unhealthy cycle of repeatedly sapping their own strength each time they have to go back on the drug

Before PS matching, patients who received semaglutide, compared with those who received dulaglutide, had a higher BMI, were less likely to receive ACE inhibitors, statins, metformin, sulfonylureas, and insulin

The consistency of GLP-1 effectiveness across alcohol, opioids, cocaine, nicotine and cannabis suggests these drugs may act on a shared vulnerability underlying addiction not on any single substance pathway

But bottom line, in this context, it contributes to cardiometabolic disease, and that means every single meal that you eat needs to be anchored around protein, fiber, and healthy fats

Am J Nephrol 2019;50:345e56
