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By contrast, those on external testosterone (Group C) saw testosterone levels go up (as expected) but their LH/FSH were suppressed, and those on gonadotropins (Group A) saw some improvement in T but not as robust as liraglutides effect

Additionally, they offer benefits like improved metabolism, cardiovascular health, and kidney health

If you are on both metformin and semaglutide or metformin and tirzepatide , pay extra attention to magnesium and B12 levels

Incretin based therapies such as GLP-1 receptor agonists have revolutionised management of type 2 diabetes by enhancing insulin secretion, slowing gastric emptying and reducing appetite (Dungan & DeSantis, 2025)

FDA labeling for these medications notes that delayed gastric emptying may affect the absorption of concomitantly administered oral medications and that they are not recommended for use in patients with severe gastroparesis