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GLP-1 acts as a satiety hormone [21], transmitting signals of fullness from the gut to the brain and activating GLP-1R mediated by paracrine activations of vagus afferent neurons innervating the gastrointestinal tract [22, 23]

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PMID: 21795304

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Providers increasingly encounter patients Read More Protecting Muscle While Treating Obesity: New Protein Targets for Older Adults on GLP-1s Jun 16, 2026 Articles, Diet and Nutrition, Exercise, Geriatric Medicine, GLP- 1 Agonist Therapy Center, GLP-1 Agonist Therapy Center, Obesity, Obesity 1,502 views The rise of highly effective GLP-1 receptor agonists and dual incretin therapies has transformed obesity treatment