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Description

We know FDA-approved weight-loss drugs in the class of medications known as GLP-1 receptor agonists have been proven safe and effective for treating type 2 diabetes, regulating blood glucose levels, helping people lose weight, and decreasing the risk of some cardiovascular diseases at established dosages

Studies link it to the hallmarks of extreme dieting: caloric deficits that cause iron, protein, zinc, and biotin shortages and hormonal shifts like elevated cortisol levels and/or insulin fluctuations

86 Fracture risk A large French cohort study involving 14 253 VSG patients reported an overall major osteoporotic fracture incidence of 1.70 per 1 000 person-years, with specific rates for distal forearm/wrist (0.82), proximal humerus (0.37), clinical vertebral (0.29), and hip fractures (0.22)

A holistic perspective considers the multifaceted nature of metabolic dysfunction and excess weight, including: Nutrition Movement Stress management Gut health Hormonal balance Environmental toxins An integrative approach is essential to maximize the benefits of GLP-1 agonists while minimizing potential side effects