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They do this by supporting GLP-1, a satiety hormone released in the gut after eating that slows down digestion and helps you feel full

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doi: 10.1016/S2213-8587(18)30024-X 35 TellaSHRendellMS

101 It is essential to examine the cardiovascular profile of GLP-1 analogs as well since DPP4 inhibitors increase GLP-1 levels
P EG ylation : Increasing the molecular size of the drug to slow enzymatic degradation