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doi: 10.1016/j.diabres.2021.108904

Cardiovascular outcome trials have demonstrated significant reductions in major adverse cardiovascular events with certain agents in this class (liraglutide, injectable semaglutide, and dulaglutide), leading to expanded indications for cardiovascular risk reduction

According to the increased expression, we could identify sDPP4 as a novel adipokine released from primary human adipocytes

In summary, GLP-1 RAs, through weight loss and the reduction of pro-inflammatory cytokines [31, 33], could provide a complementary approach to standard therapies for HS, especially in patients with obesity [36]

Natural Alternatives and Adjunctive Support with Botanicals and Nutrients Certain nutrients and botanicals have demonstrated GLP-1 agonist activity, and are not associated with the complications often seen with pharmaceutical GLP-1 drug use
