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EECs receive signals from the intestinal lumen To transduce luminal signals, EECs express specialized receptors for a host of different modalities: microbial metabolites (GPR40, short chain fatty acids), noxious stimuli (Trpa1, mustard oil and indole), stretch (Piezo2, mechanical), and even taste (TR2, bitter taste) (Nozawa et al., 2009

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No absolute contraindication exists based on current evidence, but the limited human data during lactation means most medical providers recommend consulting your obstetrician and lactation specialist before deciding

doi: 10.1186/s12933-023-01765-z 17 LocatelliJCCostaJGHaynesANaylorLHFeganPGYeapBBet al

Notably, this was true in three different BMI classes, according to the study