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First, GLP-1 receptors exist on immune cells, including macrophages, lymphocytes, and monocytes

ACSL4 deletion or treatment with liproxstatin-1, an inhibitor of ferroptosis, significantly reduced 4-hydroxynonenal (4-HNE) levels, while the level of 4-HNE in esophageal cancer tissues after radiotherapy was significantly associated with better clinical prognosis of cancer patients (257)

doi: 10.1016/S0140-6736(02)07952-7

The findings are expected to influence future clinical guidelines and expand semaglutides use in preventive cardiology, offering new hope for millions at risk of heart disease

Different weight loss medications demonstrate varying gastrointestinal side effect profiles, which can inform treatment selection for patients particularly concerned about diarrhea
