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Dual GIP/GLP-1 receptor agonists Sometimes called dual agonists or twincretins, as they activate the GLP-1 receptor plus a second receptor, called GIP (glucose-dependent insulinotropic polypeptide)

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1 Due to its longer duration of action, it is typically administered subcutaneously once weekly

Renal Protection The kidneys are susceptible to damage from prolonged inflammation and hyperglycemia