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All trials were of parallel group, double-blind design, and their mean duration ranged from 0.75 (SOLOIST-WHF) to 5.4 years (REWIND)

Competitive Landscape Orforglipron will enter a rapidly evolving competitive landscape for obesity and diabetes treatment

Available from: www.aad.org/public/diseases/a-z/hyperhidrosis-causes [accessed 26 February 2020]

In clinical trials, nausea was the most common side effect, with 16% of participants affected, based on the 0.5 mg dose (percentages vary slightly, depending on the dose)

Long-term success requires viewing semaglutide as one component of lifelong weight management rather than a temporary solution