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For instance, the FDA approved Ozempic in March 2024 to prevent heart complications in overweight and obese adults

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The meta-analysis found that tirzepatide reduced hsCRP compared to placebo with a mean difference of -32.9 (95% CI: -33.6 to -32.2)

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Adding a medication that provides renal protection through an entirely different mechanism, without additional immunosuppression, could meaningfully improve outcomes

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A documented allergy or hypersensitivity to an inactive ingredient in the FDA-approved product

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Dose increases temporarily raise the activity of GLP-1 and GIP hormones, which can intensify appetite suppression and slow digestion further until the body adapts

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