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Weight gain promotes adipocyte hypertrophy or hyperplasia, driving visceral fat deposition and shifting adipose tissue from an anti-inflammatory, angiogenesis- and lipid storage-favourable state to a proinflammatory phenotype [50]

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The topline results showed that in adults with obesity or who are overweight and have type 2 diabetes, the drug provided significant weight loss, meaningful A1C reductions, and improvements in cardiometabolic risk factors at 72 weeks

The companys defense could point out that other things in a patients life may have led to their health issues, not just Ozempic