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Chronic inflammation also develops with increased levels of tumor necrosis factor (TNF-), monocyte chemotactic protein-1 (MCP-1), C-reactive protein (CRP), interleukin-1 (IL-1), interleukin-6 (IL-6), and other pro-inflammatory cytokines, which have been found elevated in PCOS

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In the periphery, the gut is the primary site of 5-HT synthesis
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Esta hormona desempea mltiples funciones metablicas importantes: estimula la secrecin de insulina cuando los niveles de glucosa estn elevados, suprime la liberacin de glucagn (hormona que aumenta el azcar en sangre), retrasa el vaciamiento gstrico y reduce el apetito actuando sobre centros cerebrales que regulan la saciedad
