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Cell lines Hepa1-6 (mouse hepatocarcinoma cell line) and HepG2 (human hepatocarcinoma cell line) were purchased from KAC and cultured in DMEM (Wako) containing 10% FBS (Biowest)

2022;3 doi: 10.1016/j.xcrm.2022.100810

The companies sidestep the high cost associated with many name-brand drugs by using compounding pharmacies to offer cheaper, nearly identical versions of the medications

The net effect is a reduction in hunger signals originating from the hypothalamus, making it easier to eat less, resist cravings, and maintain a caloric deficit without relying on willpower alone

Manufacturers may claim these ingredients "stimulate natural GLP-1 production," but such assertions lack clinical validation