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For those with hypermobility and EDS, the specific risks around gastroparesis, muscle loss, bone health, and the already-complex GI picture mean that wait and see is a completely defensible position in 2026

Diarrhea, constipation, and decreased appetite are also common

doi:10.1038/379069a0 23

Thoughtful preparation with your doctor is the trick for both safety and true effectiveness

Similarly, whether the reduction in BP with weight loss interventions is a direct result of weight loss per se , or due to other effects of these interventions, is uncertain as is the underlying mechanisms involved
