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Psychiatry 45, 5463

The reduction of cardiovascular events is not only related to anti-diabetic properties, but also to pleotropic effects leading to the reduction of the residual cardiovascular risk, that has been defined as the risk of progression of CV events (MACE or HF) that remains after the optimal glycaemic control in T2DM patients, and it seems to be related to meta-inflammation, defined as a low-grade chronic and sterile inflammatory status

placebo [14]

When operating optimally, these hormones manage several critical functions: Appetite Regulation: They signal to your brain that you are full, helping to reduce overall hunger and cravings

Calcineurin inhibitors exert their immunosuppressive effects by binding to the nuclear factor of activated T-cells, thereby reducing the release of cytokine interleukin-2 from T cells and T proliferation