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Description
Obesity is a global health crisis, significantly increasing the risk of various chronic diseases, including cardiovascular disease (CVD)

Recently, tirzepatide (the ingredient name for Mounjaro) has seen a rapid increase in searches
Glucagon-like peptide-1 (GLP-1) is a hormone produced in the gut that is essential for regulating blood sugar levels

doi: 10.7717/peerj.17615 46 McMorrowHECohenABLorchCMHayesNWFlepsSWFrydmanJAet al

In particular, GLP1-RA counteract the action of angiotensin II (ANG II) inhibiting its synthesis, increasing the inactivation of its circulating form and contrasting its action on target tissue like glomerular endothelial cells and cardiomyocytes
