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Evans et al., 2021b)

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Furthermore, inflammatory and fibrotic mediators can directly modify atrial electrophysiology and enhance AF susceptibilityfor instance, by regulating calcium homeostasis and connexins, which are associated with AF triggers and slow atrial conduction (106, 107)

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ISF induced gastric and intestinal distension, which increased circulating GLP-1 levels and activated a subset of vagal sensory neurons (Fig

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