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These three factors combine to create the most efficient absorption surface available outside of injection
Stacking interaction with Tyr145 is present 98% of simulation time
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Although not assessed in this small study, genetic polymorphisms of metformin uptake or excretion may explain the large interindividual variations in metformin concentrations but they have not been reliably linked to metformins glucose-lowering effects [36,37,38]
Clin Gastroenterol Hepatol
