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![glp-1 and dual glp-1/gip receptor agonists GIP/GLP-1 agonists: New advances for treating type-2 diabetes PDF] Novel dual GLP-1/GIP receptor](https://ars.els-cdn.com/content/image/1-s2.0-S0003426623000045-gr1.jpg)
glp-1 and dual glp-1/gip receptor agonists GIP/GLP-1 agonists: New advances for treating type-2 diabetes PDF] Novel dual GLP-1/GIP receptor
Description
[DOI] [PubMed] [Google Scholar] 9.Koliaki C., Doupis J
![glp-1 and dual glp-1/gip receptor agonists GIP/GLP-1 agonists: New advances for treating type-2 diabetes PDF] Novel dual GLP-1/GIP receptor](https://figures.semanticscholar.org/d83a64f6b7193358c31030487761fc19c80dd33c/3-Figure1-1.png)
Scarce data exist on the outcomes of AP in patients with T2DM who are taking glucagon-like peptide-1 receptor agonists (GLP-1 RAs)
![glp-1 and dual glp-1/gip receptor agonists GIP/GLP-1 agonists: New advances for treating type-2 diabetes PDF] Novel dual GLP-1/GIP receptor](https://www.cell.com/cms/attachment/2119340205/2092424974/fx1.jpg)
Although GIP and its experimental analogs seem to have a glucagon-elevating effect, its end-action on metabolic parameters, especially when GLP-1 is present, is neutral or tilted towards benefit
![glp-1 and dual glp-1/gip receptor agonists GIP/GLP-1 agonists: New advances for treating type-2 diabetes PDF] Novel dual GLP-1/GIP receptor](https://pbs.twimg.com/media/GhhUVmWbQAA3ItX.jpg)
But their appeal doesnt stop there
![glp-1 and dual glp-1/gip receptor agonists GIP/GLP-1 agonists: New advances for treating type-2 diabetes PDF] Novel dual GLP-1/GIP receptor](https://cdn.drugdiscoverynews.com/assets/image/4648/screenshot-2025-11-03-152640-m.png)
Rybelsus patients lost between 2.5% and 4.1% of their body weight on average
![glp-1 and dual glp-1/gip receptor agonists GIP/GLP-1 agonists: New advances for treating type-2 diabetes PDF] Novel dual GLP-1/GIP receptor](https://www.mdpi.com/medicina/medicina-60-02030/article_deploy/html/images/medicina-60-02030-g001.png)