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But as researchers at Yale have pointed out, patients pursuing unvalidated microdosing protocols are essentially serving as their own test subjects on both efficacy and safety

By potentially modulating the central nausea response and simultaneously preventing the nutrient deficiencies that GLP-1 therapy can create, B12 helps patients stay on their prescribed dosing schedule without the interruptions and dose reductions that nausea typically forces

Some people with severe obesity were even able to reach an average weight loss of 85 pounds after two years