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During this adaptation phase, thyroid hormone (T3) levels may decline modestly, resting metabolic rate slows, and mitochondrial energy production adjusts

Steve Small: Yeah, well, thats a good question because looking into this, Don, I did find a recent observational study back in November 2025 that looked at over 400,000 patients taking GLP-1 agonists such as semaglutide to see if they had a higher risk of the side effect

Bruce Liu, a partner at global consulting firm Simon Kucher & Partners, told Insider that "community clinics and qualified online hospitals" are allowed to prescribe medication too

Protein Support Protein is one of the most important nutrients to maintain while using GLP-1 medications
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