.85 mg semaglutide Weight-loss jab could be made for $3 a month, study finds | Global health Semaglutide is similar to a natural hormone in your body (incretin) Weight loss drug could reduce

Retatrutide helped patients lose 24.2% of their body weight, or 58 pounds, on average after 48 weeks in a midstage trial on adults who were obese or overweight

Additionally, it must be discontinued at least 2 months before a planned pregnancy because of its long washout period

In some cases, if side effects become too severe, your doctor may suggest switching to a different medication or adjusting the dosage

It usually subsides within days to weeks as the body adjusts

The graphic below shows the degree of weight loss from each intervention, although the newer GLP-1s are likely to lead to similar weight loss to bariatric surgery