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I GLP-1 RA non sono considerati una terapia di prima scelta per la maggior parte dei pazienti con diabete di tipo 2, bench sia consigliata l'aggiunta precoce di questi farmaci in pazienti selezionati con malattie cardiovascolari e/o nefropatie

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Patients face these permanent life-altering consequences from NAION-related blindness: Sudden blindness in affected eye: Most experience dense altitudinal visual field loss affecting top or bottom half, with some suffering complete blindness Inability to drive or work: Vision loss severe enough to disqualify from driving and render many occupations impossible Constant risk to fellow eye: Living with approximately 15% risk over five years that the second eye will suffer identical fate No restorative treatment options: Unlike cataracts, NAION leaves patients with zero medical solutions for recovery Permanent disability from NAION has made these injuries central to litigation