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Semaglutide for managing overweight and obesity (TA875) Resource impact report

Durability of histological response and rebound effects A critical unresolved question concerns the durability of histological improvement following treatment interruption or dose reduction

doi: 10.1158/2159-8290.CD-21-0407
A realistic way to think about GLP-1 medications: They improve the environment around lipedema (not the diseased tissue itself) GLP-1 belongs in the category of supportive tools similar to anti-inflammatory diet, metabolic care, and mobility support
Given our current understanding that DHEAS acts as a GABA A receptor antagonist, it is unclear how blocking the GABA A receptor channel blocked the neuroprotective effect of DHEAS