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[25] Prospective data demonstrate a modest increase in venous-thromboembolism incidence from roughly three to eight events per ten-thousand woman-years, particularly during the first treatment year and in women older than sixty, reinforcing the value of periodic risk re-appraisal

Accelerated weight loss can lead not only to rapid fat loss but also to lean muscle loss

Do not use: if you have bloody or black stools if you have difficulty swallowing Ask a doctor before use if you have: fever mucus in the stool a history of liver disease a history of abnormal heart rhythm Ask a doctor before use if you are taking a prescription drug

Secretion of incretin hormones and the insulinotropic effect of gastric inhibitory polypeptide in women with a history of gestational diabetes

You should seek medical advice promptly if you experience: Severe or persistent abdominal pain , especially if accompanied by fever or vomiting seek urgent medical attention if severe and persistent Signs of gastrointestinal bleeding black, tarry stools, blood in vomit, or vomit resembling coffee grounds call 999 or go to A&E immediately Severe, persistent nausea or vomiting that prevents adequate fluid or food intake, risking dehydration and potential kidney problems Symptoms of pancreatitis severe upper abdominal pain radiating to the back stop taking Ozempic and seek urgent medical attention Jaundice (yellowing of skin or eyes) or pale stools, which may indicate gallbladder or liver problems Unexplained, rapid weight loss or inability to maintain adequate nutrition Patients should contact their GP or diabetes specialist nurse if gastrointestinal side effects persist beyond the first few weeks of treatment or significantly impact quality of life