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& Gautier, J
Ozempic (semaglutide) is a synthetic drug that mimics a hormone called GLP-1 (glucagon-like peptide-1)
Understanding this distinction is essential for setting appropriate patient expectations regarding how these medications facilitate weight reduction
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In cellular assays measuring cAMP accumulation, orforglipron achieves approximately 60-80% of the maximal response produced by GLP-1, depending on the assay system and receptor expression levels
