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Obesity has an even greater impact on SM function and composition

Tirzepatide is the newest FDA-approved prescription medication that helps treat type 2 diabetes and obesity

Studies have shown that insulin resistance in the brain contributes to dopaminergic neuron vulnerability, promoting oxidative stress, mitochondrial dysfunction, and protein aggregation (55)

If symptoms persist, medical guidance is recommended

JCI Insight 2020;5(12):e137495
