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Over time, patterns may emerge that can help you pinpoint the culprits

For those managing diabetes or seeking weight loss options, Wegovy or metformin may be potential options

Mild GI effects (nausea, fullness) as your body adapts

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Importantly, comorbid T2DM or elevated peripheral IR accelerate disease progression in AD and PD independently of vascular disease, with higher peripheral IR predicting conversion from mild cognitive impairment to AD (12, 13) and faster motor and cognitive decline in PD (14, 15), thereby implicating IR as a modifier of NDD biology rather than a simple comorbidity