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Adults (aged 18 years) with a BMI 27 kg/m 2 and glycated hemoglobin (HbA 1c ) of 710% (5386 mmol/mol) were randomly assigned (1:1:1), to receive either once-weekly, subcutaneous tirzepatide (10 mg or 15 mg) or placebo for 72 weeks
Wait exactly 30 minutes before eating, drinking, or taking any other medications
CAPAs must define measurable success criteria
Superiority in reducing A1C was concluded for each dose of SEM compared with placebo, when the upper limit of the two-sided 95% CI for the estimated difference was below 0%
