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Its also important to note that the adjustment period varies from person to person

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After the run-in period, those with inadequate glycemic control (A1C 6.5% to 10%) were randomized 1:1 to the addition of sitagliptin 100 mg once daily or glipizide for 52 weeks

Sasaki-Hamada, S., Ito, K
GLP-1 receptor agonist medications were originally used to treat type 2 diabetes