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Neuroprotective effects of GLP-1R agonism GLP-1R agonists improve cerebral blood flow (CBF): By enhancing neurovascular coupling, these drugs ensure that blood flow is properly regulated in response to brain activity, improving overall brain function, particularly in obesity and metabolic disorders

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doi: 10.1128/AAC.48.8.2787-2792.2004

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People whose BMI is 40.0 or greater are sometimes categorized as severely obese. The CDC has more information about BMI, its uses and how to calculate it
