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Steve Bloom in the U.K., began to publish what they'd observed in clinical trials that patients treated with GLP medicines for their diabetes were also losing weight

This was evident in the LIVE and FIGHT trials, in which liraglutide, despite leading to significant weight loss compared with placebo, failed to demonstrate any beneficial effects on clinical outcomes or left ventricular ejection fraction (LVEF) in patients with HFrEF

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Previous studies have suggested weight-loss drugs may improve heart failure symptoms, but their effect on important outcomes such as hospitalisation and death has never been evaluated in large populations until now

NAD+ plays a role in how your cells produce energy, repair damage, and regulate metabolism