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AASLD 2017 Current Status of Pharmacologic Treatments for NASH No approved therapies for NASH Currently available therapeutics with (some) proven efficacy Vitamin E Pioglitazone NASH: targets for therapeutics Endpoints for clinical trials Disease Activity (steatohepatitis) = NAFLD Activity Score (NAS) Disease Progression = Fibrosis Stage Clinical outcomes : Cirrhosis (MELD, Portal hypertension), Liver-related outcome, death Adapted from Konerman MA

Wegovy pens are white single-dose prefilled injectors with color-coded labels: green (0.25 mg), pink (0.5 mg), brown (1 mg), blue (1.7 mg), and black (2.4 mg)

Shortly, after the war ends, they develop a new product called Lente Insulin, which is slower acting Insulin, which means it's thus longer lasting

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Alfaris said gastrointestinal adverse events were more common with orforglipron than placebo and were consistent with those seen in other incretin-based drugs