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Proton magnetic resonance spectroscopy ( 1 H MRS), with its extremely high sensitivity, is used for detecting and quantifying several endogenous tissue metabolites in a single acquisition, but it is not capable of tracking the activity of a metabolic pathway due to limitations related to water, lipid suppression, and magnetic field homogeneity [22]

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In addition, the choroid plexus and adipose tissue both produce tryptase, which can induce mast cell activation, ultimately leading to increased intracranial pressure

As the body gets used to the medication, these side effects typically diminish or disappear