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Del PratoSRosenstockJGarcia-SanchezRIqbalNHansenLJohnssonEet al
Sanofi) and Trulicity (dulaglutide

these factors may contribute to a higher incidence of hepatobiliary adverse events [2,37]

doi: 10.1152/ajpendo.00665.2010

It has been suggested that in obese patients, these adipokines act peripherally, causing lipid accumulation, lipotoxicity, endoplasmic reticulum stress, mitochondrial dysfunction, and ultimately, cell apoptosis [111,112,113]
