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Despite its beneficial effect on body weight and metabolic parameters, the lipase inhibitor Orlistat also produces deficiencies in liposoluble vitamins [144,145]

The fix: eat protein first at every meal

The proglucagon gene (gcg) encodes for glucagon as well as two glucagon-like peptides, GLP-1 and GLP-2 ( Figure 2 summarizes the tissue-specific post-translational processing of proglucagon by PC1/3 and PC2, the resulting peptide products, and their receptor targets

Zepbound (tirzepatide) is a glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist that is FDA-approved along with increased physical activity and a reduced-calorie diet for chronic weight management in adults with a starting body mass index (BMI) of: 30 kg/m^2 or higher (obesity) or 27 kg/m^2 or higher (overweight) with at least one weight-related condition such as high cholesterol, high blood pressure (hypertension), type 2 diabetes, heart disease, or obstructive sleep apnea