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Studies demonstrated that the fat-damaging effects of GLP-1 are effective for weight loss and may also improve insulin resistance in obese patients [95]

SGLT2 inhibitors provide substantial benefits for people with type 2 diabetes mellitus and either established HF or elevated HF risk [86]

Once inactivated, insulin secretions stop, and glucagon, the hormone responsible for increasing blood sugar levels, is also suppressed[3]

Exendin-4 therapy still offered an additional benefit on reducing transverse aortic constriction-induced cardiac hypertrophy-caused myocardial damage in DPP-4 deficient rats

Park SW, Mansur RB, Lee Y, et al