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As GLP-1 therapies advance, semaglutide's established efficacy and adaptability continue to define its role as a leading option for medically supervised weight loss in 2026

But some telehealth companies are marketing GLP-1s as an easy way to lose weight sometimes with the help of paid celebrity endorsements without emphasizing the importance of healthy eating and exercise, she said

Muscle Preservation Strategies During GLP-1 Weight Loss Muscle loss during GLP-1 therapy typically results from calorie deficit and reduced protein intakenot from the medication itself

This happens because the body fights weight loss by: Increasing hunger hormones Reducing metabolism Increasing cravings Conserving calories Obesity is therefore a biological disease rather than a simple lifestyle issue