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If new or severe symptoms appear after a dose change, pause and consult your provider before continuing

An ongoing early feasibility trial (ClinicalTrials.gov registration NCT03868670) has recruited participants with treatment-refractory obesity and loss-of-control eating to identify related iEEG activity 23

These check-ins allow your provider to monitor your progress, evaluate tolerability, and adjust dosing when medically appropriate

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However, because letrozole can impact metabolism and Ozempic affects digestion, you should only use them together under the close supervision of a licensed healthcare provider