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Jul 4 2023;12(13):e029852

Moreover, evidence suggests that this dual action might account for the fact that Mounjaro appears to be somewhat more effective than Wegovy

The key objective of SOUL was to demonstrate that oral semaglutide lowers the risk of major adverse cardiovascular events (a composite endpoint consisting of cardiovascular death, non-fatal myocardial infarction and non-fatal stroke) compared to placebo, both added to standard of care in patients with type 2 diabetes and established CVD and/or CKD

Finally, the remaining papers studied patients with alcohol use disorder (2), anorexia nervosa (1), acquired hypothalamic damage (1), Prader-Willi syndrome (1), and major depressive disorder (1)

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