glp 1 or metformin Frontiers GLP-1 Agonists: Increasing Effective Insulin
Description
DPP-4 inhibitors do not have significant effects on GI motility or appetite that are observed with more efficacious (DPP-4 resistant) GLP-1 agonists

Most show long-term benefits with manageable risks

Pre-filled pen devices versus vial and syringe Pre-filled pens (Ozempic, Wegovy, Mounjaro, Zepbound) simplify the injection process significantly

The relative importance of GIP and GLP-1 may vary depending on meal composition and diabetes stages

It is an unusual dynamic
