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Some patients experience temporary plateaus lasting 12 weeks, which is normal and reflects your body's metabolic adjustment rather than treatment failure

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Originally developed for diabetes and weight loss, GLP-1 medications may help quiet the brains reward circuitry, muting the intense craving signals associated with Substance Use Disorders

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Interestingly, appendicular BMD, but not axial BMD, was not reduced despite significant weight loss in the semaglutide group and no changes in BTMs or bone microarchitecture was encountered [70]

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