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The surge in demand for GLP-1 medications for weight loss has shifted how healthcare providers approach weight management conversations.

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From a mechanistic perspective, the findings reinforce the concept that GLP-1 receptor agonists exert cardiovascular benefit beyond glucose lowering, likely through integrated effects on endothelial function, inflammation, and metabolic regulation

The use of this medication in patients with severe renal impairment or on dialysis is not recommended
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