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(2.3) For indications in adults related to heart failure and chronic kidney disease the recommended dosage of dapagliflozin is 10 mg once daily

GLP-1s are thought to cause higher muscle loss (2539%) than non-pharmacological methods of weight loss, such as diet and exercise (10-30%) 29

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Tirzepatide (a GLP-1/GIP dual agonist) produces slightly greater initial weight loss than semaglutide in trials, but both show similar rebound patterns when discontinued

Food and Drug Administration (FDA) as the brand name drugs do
