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Liraglutide gained Food and Drug Administration (FDA) approval on December 23, 2014, as a treatment option for chronic weight management [25]

In animal studies, GLP-1RAs consistently reduced drug intake, weakened dopamine release in reward neural networks, and reduced the probability of relapse

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This is usually mild but worth monitoring

Early-stage research has demonstrated that microneedle technology can deliver peptides like semaglutide in animal models
