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Activation of GLP-1R by GLP-1 or other exogenous agonists, including exendin-4 and liraglutide, decreases inflammatory responses in several animal models like rat heart and whole animal model

GLP-1 medications are designed to be used as part of a broader weight management approach - including lifestyle modifications - not as standalone interventions

Injecting in the morning means that peak drug activity, and therefore peak GI effects, occurs during the daytime when you are active and can manage symptoms more easily

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This exclusion has been in place since the Part D prescription drug benefit launched in 2006